Soluble-iron-albuminate preparation.



more]; STATES r TENT oFFIoE,

ERNS LAWS, OF mum on, GERMANY.

SOLUBLE-IRONf-ALBUMINATE PREPARATION.

Specification of Letters Patent.

Patented J uly 27, 1909.

Application filed May 14, 1906. Serial No. 316,824.

To all whom it may concern:

Be it known that,- I, ERNST LAVES, chemist, subject of the Emperor ofGermany, and resident of Militiinstrasse, Hanover, Germany. haveinvented new and useful Improvements in and Relating to Soluble-Iron-Aibuminate Preparations, of which the following is a specification.

This invention relates to'a recipe for pre paring easily solubleiron-.albuminate and iron albuminate solutions which will retain theirperfect integrity.

In the first instance iron albuminate is prepared in the already knownway, from solution containing combined iron oxid, for instance 30kilograms either of solution of oxiehlorid of iron, or solution ofdialyzed iron, which are too solutions of basic ferric ehloridcontaining about of ferric oxid, which is mixed (at 50 centigrade) with200 liters of water with carbonate of potassium 3 to 5 grams of alkalito l kilogram of oxychlorid of iron, and mixed with a solution of- Skilograms of dry albumen dissolvcd in 200 liters of water at 50centigrade. The albumen may be obtained from the white of eggs, bloodalbumen, or vegetable albumen.

3y the use of the stated quantities of material as aforementioned,about- 18 pounds of iron albumin-ate are. formed This is mixed in a dryoridamp state with (i kilograms of StltKlltlIffltHl ()Xl(.l of iron (amixture of fresh iron hydroxyd w th sugar maybeused instead of thelatter,) and 300 grams of earbonate of potassium. By means of thisaddition the qualities of the iron albumin'ate are chal'igedconsiderably namely: the albuminate has become more easily soluble, i:e. the alkali addition necessary for the dissolving can, in proportionto the addition he (l0 creased or dispensed with,

Iron allruninate solutions obtained by n'ieans of saccharaled oxid ofiron in water and spirits of wine a re durable, which is not-- the easewith theanalogue of simple albuminate solutions; the latter generallyrelatinize after being kept a short time. I

The solutions of iron albuminate obtained by alkali have an alkalinetaste and color litmus blue; if the solution is obtained with ironsaeeha rate, it is not alkaline and has no taste.

In order to dissolve iron a'lbuminat, ac-

cording to the prescription of the Deutsche zl'l'ZilGfll'lllh to makeliquor ferri albuminate, a slightly dull liquid seen in a reflectedlight, one adds approximately 15 parts of sodium-hydlroxyd to 100 partsof ironof the albuminate; according to the prescription of the jlmrm(d emm Heloetp'ca even approximately 27 parts of soditnnhydroxyd; accordingto the direction of Dietrich, Helfenberg, 45 parts of sodiumhydroxydwhen using dry iron albuminate for the purpose of obtaining a clearsolution.

By adding saccharated oxid of iron to the freshly prepared ironalbuininate, prepared in accordance to tl'ieDeutsc-he Arzneibuch,

one obtains clear solutions by the addition of 10 or 5 or 1 partsrespectively of sodiumhydroxid to 100 parts of iron of the albuminate inthe presence of 50, 100 01'150 parts v i respectively of iron of thesaccharated OXld':

of iron.

"The taste of iron in iron albuminatesam cha'rated oxid of ironsolutions is still less than in iron albuminate solutions.

l'laring fully described my invention, that I claim and desire to secureby Letters Patent is:

The process of makingthe' hereinbefore described preparation oriningstable aque- I ous solutions and eontain ng'a. chenncal'com-.

ERNST LAVES.

\Vitnesses:

l ll'INRY J. FULLER, A N NA l)! Penn.

